South Carolina 500 | 

Dr. Jerome Aya-ay

Organization
Palmetto Proactive Healthcare
Title
M.D.

Jerome Aya-ay earned a Bachelor of Science in Biology from the University of Notre Dame before pursuing a Master of Science in Biomedical Sciences and Doctor of Medicine from Marshall University School of Medicine.

His entrepreneurial spirit emerged early — in the 1990s, he ran a food delivery business from his parents’ garage in Parkersburg, West Virginia. That venture, along with working at a tanning salon where he learned business fundamentals, shaped his path toward independent health care.

Today, Aya-ay leads Palmetto Proactive Healthcare, a 20-employee practice focused on accessible, transparent care. He champions a model prioritizing clear pricing and personal attention over the complexity and hidden costs in modern healthcare.

Beyond his practice, Aya-ay serves as President of the Upstate Medical Independent Medical Association, President Elect of the South Carolina Academy of Family Physicians and Trustee for District 3 of the South Carolina Medical Association. He also serves as Associate Clinical Professor at Via College of Osteopathic Medicine.

Reflecting on leadership, Aya-ay said, “You can burn the candle at both ends and fade fast, or shine bright enough to ignite the ambitions of others.”

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The South Carolina 500 is the definitive guide to the most influential people driving South Carolina economy. Spanning industries from healthcare and finance to construction, law, and education, this statewide list brings together top leaders recognized for their impact, innovation, and leadership across sectors.

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