South Carolina 500 | 

Tonya M. Matthews

Organization
International African American Museum
Title
President and CEO

Tonya M. Matthews leads the International African American Museum as president and chief executive officer, overseeing an 80-employee institution achieving $197 million in annual economic impact since opening in 2021.

Matthews holds a doctorate in biomedical engineering from Johns Hopkins University and a bachelor’s degree in biomedical and electrical engineering from Duke University. Under her leadership, the museum hosted President Joe Biden and Supreme Court Justice Ketanji Brown Jackson, earned recognition as one of Time Magazine’s 100 World’s Greatest Places in 2024, and joined the UNESCO Network Places of History and Memory.

“Master the art of how to rest on the run,” she says, advice from a mentor about recognizing rejuvenating moments within meaningful work.

Her first position as a science museum project manager taught her that budgets need not constrain creativity.

Matthews serves on the Bright Focus Foundation board and Hilton Head Futures Advisory Board. She defines success through her successors and the impact of those she mentors.

An anime and animated film enthusiast, Matthews finds both calm and inspiration in vivid illustrations and imaginative storytelling.

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The South Carolina 500 is the definitive guide to the most influential people driving South Carolina economy. Spanning industries from healthcare and finance to construction, law, and education, this statewide list brings together top leaders recognized for their impact, innovation, and leadership across sectors.

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